The Colorado Section of the American Chemical Society
December Meeting and Special Event
Botanical Drugs-Back to the Future?
James D. McChesney, Ph. D.
Founder and Principal, Arbor Therapeutics, LLC
Monday, December 9, 2013
5:30 p.m. – 8:30 p.m.
5:30 p.m. Social Hour and Butterfly Viewing at “Wings of the Tropics Conservatory”
6:30 p.m. Buffet Dinner
7:30 p.m. Presentation
Natural Products have historically provided leads for discovery/development of new pharmaceuticals, especially anti-infectives and chemotherapeutic agents. In the last couple of decades the pharmaceutical industry has moved to an alternate strategy of combinatorial synthesis and high-through-put screening of compound libraries for discovery. However, this strategy has largely been unproductive and companies find their “pipelines” more and more depleted. New strategies and paradigms need be found to make new pharmaceutical discovery and development more productive.
The phenomenon of “Drug Resistance” is recognized as a major challenge to the continued health of humankind. We are rapidly exhausting our options for antibiotic therapy of infectious diseases. We have only a single class of anti-parasitics (the artemisinin derivatives) to treat drug resistant malaria and recent clinical observations of developing resistance to these agents have been reported. Other infectious parasitic diseases are largely untreatable with today’s therapies. Cancer chemotherapy has not led to permanent remissions (cures) due to development of drug resistance. Does the careful and systematic evaluation and development of natural mixtures (Botanical Drugs) have promise to provide effective therapies? There are suggestions the answer is yes, maybe an emphatic yes, when one examines the evidence given us from ecological interactions.
Reservations must be made for dinner by COB on Saturday, Nov. 30th. To reserve a dinner contact: Marge Rakowsky at email@example.com or by phone at 303-770-7121 or text message 303-829-7121. Dinners (including a drink ticket) are $30 for members and guests and $15 for students or retired members.
This year the section will vote on installation of new bylaws. Please read the proposed bylaws by clicking this link.
Please check who is one the ballot here Election Candidates and bylaws.doc
Dan Branan has thrown his hat into the ring to run for Chair Elect for 2014, Chair for 2015, and Past Chair for 2016. His bio can be found here: Branan_BioACS.docx